NCA user interface description

Main Mappings panel

Dosing panel

Slopes Selector panel

Slopes panel

Partial Areas panel

Therapeutic Response panel

Units panel

Parameter Names panel

Options tab

User Defined Parameters tab

Rules tab

Plots tab

Main Mappings panel

Mappings panels identify how input variables are to be used. Map the data by dragging the dataset from the Data folder to the Setup tab or use the icon_select_source icon in the Setup tab.

Once a dataset is mapped, use the option buttons in the Mappings panels to assign the columns in the dataset to the appropriate context associations. Required context mappings are colored orange.

None: Columns mapped to this context are not included in any analysis or output.

Sort: Categorical variable(s) identifying individual data profiles.

Carry: Variable(s) to copy to the output worksheets.

Note that time-dependent data variables (those that change over the course of a profile) are not carried over to time-independent output (e.g., Final Parameters), only to time-dependent output (e.g., Summary).

Plasma study 

Time: Relative or nominal dosing times used in the study.

Concentration: The measured amount of a drug in blood plasma.

(Plasma Models with Sparse Sampling also require a single Subject mapping.)

Urine study 

Start Time: Starting times for individual collection intervals during a urine study.

End Time: Ending times for individual collection intervals during a urine study.

Concentration: Dependent variable, drug concentration in urine.

Volume: Volume of urine collected per time interval.

Drug effect study 

X: Time values for the drug effect data.

Y: Drug effect or response values.


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