The Structure tab is used to set up the structural level of a model and it is available to both built-in and graphic modes. When selections are made in this tab, the PML that defines the model changes. The changes to the PML can be viewed in the Model Text tab.
The following discussion of the Structure tab pertains only to built-in models. The description of this tab for graphic models can be found in the “Graphical model interface” section.
Structure model options tab set up for a PK intravenous population model
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In the Type menu, select the type of Maximum likelihood model:
PK: See “PK model options”.
Emax: See “Emax model options”.
PK/Emax: The options for the PK and Emax portions of the model are the same as those listed under “PK model options” and “Emax model options”, respectively. The other options are listed under “PK/PD model options”.
PK/Indirect: See “PK/Indirect model options” for Indirect model options. The options for the PK portion of the model are the same as those listed under “PK model options”. The other options are listed under “PK/PD model options”.
Linear: See “Linear model options”.
PK/Linear: The options for the PK and Linear portions of the model are the same as those listed under “PK model options” and “Linear model options”, respectively. The other options are listed under “PK/PD model options”.
Caution:Changing the structural model after random effects have been set up can result in reordering of the random effects. Caution is advised in double-checking the random effects entries after a model is changed.
Structure tab options change depending on the type of model selected.
