Emax model options

Check the Baseline checkbox if the model has a baseline response.
A new parameter, E0, is added to the baseline response and the Fractional checkbox is made available.
Check the Fractional checkbox if the Emax model is fractional.
Selecting this option modifies the E0 equation statement.
Check the Inhibitory checkbox if the Emax model is inhibitory.
The structural parameters EC50 and Emax change to IC50 (concentration producing 50% of maximal inhibition) and E0 (baseline effect).
Check the Sigmoid checkbox if the Emax model is sigmoidal.
A shape parameter, Gam, is added.
In the Residual Error field, define the equation used to determine the error model.

•E in the residual error model represents the effect observation.

•Changes made in the Residual Error field are shown in the observe statement.

In the first field, type the name of the observed effect variable or accept the default name of EObs.
In the second field, type the name of the epsilon variable or accept the default name of EEps.
In the error model type menu, select the type of error model. Refer to “Additional details on residual error models” in the PK model section for more information.
Check the BQL? checkbox if the dataset contains BQL values for the observation data. Refer to the BQL? description in the PK model section for more information.
In the Stdev field, type a value for the standard deviation.
Check the Freeze checkbox to freeze the standard deviation to the value shown in the Stdev field.