Phoenix Installation and Licensing

This section contains installation instructions and licensing information for the Phoenix platform and its modules, such as Phoenix NLME, the IVIVC Toolkit. The generic term Phoenix is used to simplify terminology.

Topics in this section include:

System and hardware requirements

Installing Phoenix

Post-installation considerations

Silent installation of Phoenix

Phoenix 64-bit versus 32-bit version

Licensing of Phoenix software

Testing the Phoenix installation

Test installation of Phoenix NLME

System and hardware requirements

Phoenix is a software platform built on the Microsoft .NET 4.7 framework. It uses the MinGW (Mini­malist GNU for Windows) compiler to create PML (Phoenix Modeling Language) models. Phoenix also uses MPICH2 to allow usage of multiple CPUs and CPU cores. All software prerequisites needed to use basic Phoenix functions are included in the Phoenix installation file. Extended Phoenix func­tions have additional software requirements.

Phoenix NLME-specific information

GNU compilers are 64-bit version 4.9.x and the MPI version is 1.4.1p.

Phoenix NLME only works on 64-bit systems.

NLME jobs can be executed on remote Linux hosts and Torque/SGE grids from a Phoenix Windows installation.

If user accounts have limitations in executing command prompt commands, users will not able to exe­cute NLME objects. The Prevent access to the Command Prompt policy for users must be changed from Enabled to Disabled.

Required software

Windows® Installer 3.1 can be downloaded through the Microsoft Update service or by downloading the Windows Installer 3.1 redistributable from the Microsoft download page.

A PDF reader, such as Adobe Reader, must be installed to access PDF files of the User’s Guides and various software documents, such as the Validation Suite report.

Compatibility with operating system versions

Phoenix is compatible with the following desktop operating system versions with the indicated lan­guage packs with a Regional Options setting of English (United States):

Compatible operating systems

Operating Systems

Languages

Windows 7 SP1 (32 and 64-bit*)

English (United States), Kanji (Japan),
French (France), Spanish (Spain),
German (Germany), Simplified Chinese (China)

Windows 8.1 (32 and 64-bit*)
Update KB2919355,
using a keyboard and mouse,
both Professional and Enterprise editions;
not RT (Mobile),
not on a tablet

English (United States), Kanji (Japan),
French (France), Spanish (Spain),
German (Germany), Simplified Chinese (China)

Windows 10 (64-bit) version 1607 or greater,
using a keyboard and mouse,
Professional edition

 

*Phoenix NLME only works on 64-bit systems.

Phoenix is compatible with the following server operating system versions (for direct access or for access via a desktop with a terminal server application), with English (United States) operating sys­tem/language pack and Regional Options setting of English (United States):

Compatible versions of server operating systems

Windows Server 2008 R2 SP1 (64-bit)

Windows Server 2012 R2 Update KB2919355 (64-bit)

Windows Server 2016

Windows Server 2019

Note:Phoenix is a desktop application that requires isolated resources in order to perform optimally. If you wish to deploy this desktop application in an enterprise type fashion, such as through Citrix, it is important that it be done in a manner that will isolate the recommended amount of resources to each user, such as through a VDI (virtual desktop infrastructure). Publishing Phoenix from a shared resource server with multiple users is not recommended.

Compatible third-party software

Third-party tools that are to be used as plug-ins need to be installed on the server. The following third-party software programs are compatible with Phoenix.

Compatible versions of third-party applications

Microsoft Office 2010, 2013, 2016, 2019
local installation and usage of Office 365 (32 and 64-bit).
Web version of Office 365 is not compatible with Phoenix for the tools that use Office.

SAS: versions up to and including 9.4 (32 and 64-bit)

NONMEM: 7.1.2, 7.2, and 7.3 (32 and 64-bit)

SigmaPlot as a third party tool: 11.1 through 12.5

SigmaPlot as used by AutoPilot Toolkit 2.x for Phoenix: 11.1, 11.2, 12.2, 12.3, and 12.5

R for the R object and for Linux Grid computing: versions up to and including 3.6.0

R for Windows MPI-cluster processing for NLME: R 3.6.0.

PsN: versions up to and including 4.7.0 (only with the operating system ver­sion(s) and NONMEM version(s) with which each PsN version is compatible).
Note: PsN 3.4.2 and 3.6.7 are not compatible with server operating system ver­sions or with German, Spanish, or Chinese language operating system ver­sions/language packs.

See also “Phoenix 64-bit versus 32-bit version”.

Note:When Phoenix is installed and configured to run on a Windows operating system version where its Regional Language settings are not US English, SAS and SigmaPlot objects cannot be executed.

Compatible Certara software

Phoenix can be installed on the same computer with other current Certara software products.

It is not guaranteed that a project created with a newer version of Phoenix can successfully load on older versions of Phoenix. The system will warn the user if the project cannot be loaded. The opposite (backwards compatibility) is guaranteed, although, in some cases, settings or models are automati­cally updated to new options. Warnings are given when these automatic updates occur and the user should review the loaded settings and model.

Note:Newer versions of Phoenix NLME might fail when they are executed on a grid/remote Linux sys­tem that has older versions of Certara.NLME8 installed. Check that the version of the R library package Certara.NLME8 on the remote host is the same as the package distributed with the Phoe­nix version you are installing and upgrade, if necessary (see “Job control for parallel and remote execution” for instructions).

Hardware requirements

Minimum and recommended hardware requirements

Item

Minimum Requirement

Recommended
(especially for large datasets and projects)

Processor

Intel i5 processor 3 GHz

Intel i7 processor 4 GHz

RAM

8 GB of RAM

16 GB of RAM

Internal Storage Device

1 GB 7200 RPM Magnetic HD

1 GB SSD

 


Last modified date:6/26/19
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