Deconvolution

Deconvolution is used to evaluate in vivo drug release and delivery when data from a known drug input are available. Phoenix’s Deconvolution object can estimate the cumulative amount and fraction absorbed over time for individual subjects, using PK profile data and dosing data per profile.

Use one of the following to add the Deconvolution object to a Workflow:

Right-click menu for a Workflow object: New > NCA and Toolbox > Deconvolution.
Main menu: Insert > NCA and Toolbox > Deconvolution.
Right-click menu for a worksheet: Send To > NCA and Toolbox > Deconvolution.

Note:To view the object in its own window, select it in the Object Browser and double-click it or press ENTER. All instructions for setting up and execution are the same whether the object is viewed in its own window or in Phoenix view.

User interface description
Results
Deconvolution methodology
Deconvolution example