Note: To run a model through use of the nmfe script supplied with NONMEM, you have to instruct Pirana as to the location of the NONMEM installation. This is done by setting up profiles using the Settings dialog (see the “NONMEM” section of the Settings dialog description).
If you are running NONMEM through PsN, the location of NONMEM is already specified in the psn.conf file of PsN.
Select the model(s) to run.
Right-click the selected model and choose nmfe.
Or
Click 
in the toolbar.
Or
Use the Control-R keyboard shortcut.
The Run window contains a number of additional options for running the model(s).
The Run directory shows the path specified in the Folder field on Pirana’s main page.
Check the Run in separate folder(s) box to create individual folders, prefixed by “nmfe_”, for each model execution.
Check the Run multiple models in parallel box to allow parallelized executions.
If unchecked, the models will execute sequentially.
Check the Copy back results to main folder box to bring the results from parallel runs back to the main folder.
This option is only available when the Run multiple models in parallel box is checked.
From the Hosts pull-down, choose the host on which to run the job. (Refer to “Pirana and Remote Hosts” for details on setting up a remote host in Pirana.)
If the chosen host has job schedulers associated with it, select the scheduler to use from the second pull-down.
Select the NONMEM installation from the pull-down.
Click + to locate a NONMEM installation that is not listed on the pull-down.
Choose the configuration file to use for the parallelization and the number of nodes to use from the two pull-downs.
Parallelization configuration files can be generated using the NM parallelization file wizard in Pirana.
You can also have Pirana generate the parafile on-the-fly (select auto-MPI or auto-FPI from the Parallelization file menu). In the Settings dialog, in the NONMEM > MPI settings and NONMEM > FPI settings tabs, set up the MPI and FPI files that Pirana generates on the respective tabs. (See MPI settings for parallelization and FPI settings for parallelization.)
Parallelization files can be imported from local or remote locations. Local import can be performed through the Central parafiles location option in the NONMEM tab of the Settings dialog. Remote parallelization files can be imported from a host location using the Remote location of parallelization files option in the NONMEM > Hosts > <remote host name> sub-tab of the Settings dialog.
Press Command line arguments (nmfe) to toggle expanding the dialog to view and optionally add nmfe command line arguments to include in the job execution.
Press Show start script to toggle expanding the dialog to view and optionally edit the model execution script and command line changes for the run options selected.
Uncheck the Close this dialog window after starting run box to keep the dialog open.
Press Run to submit the job for execution.