Phoenix’s IVIVC object supports specification and running all or a subset of operations required to create an IVIVC model, validate it, and use it to make PK predictions, i.e., it is not necessary to execute the entire object during the IVIVC modeling process. When an IVIVC object is executed, however, all IVIVC steps will run.
Use one of the following to add the object to a Workflow:
Right-click menu for a Workflow object: New > IVIVC > IVIVC.
Main menu: Insert > IVIVC > IVIVC.
Right-click menu for a worksheet: Send To > IVIVC > IVIVC.
To view the object in its own window, select it in the Object Browser and double-click it or press ENTER. All instructions for setting up and execution are the same whether the object is viewed in its own window or in a Phoenix view.
This section contains the following topics:
InVitro setup
InVitro Formulation mapping panel
InVitro Estimates mapping panel
InVivo setup
Correlation Estimates mapping panel
Prediction setup
Prediction Dosing mapping panel
Prediction Estimates mapping panel
Sigmoidal and Dissolution models
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