Worksheet output

Worksheet output contains summary tables of the modeling data and a summary of the information in the Core Output. The worksheets present the output in a form that can be used for reporting and further analyses. The results worksheets are listed on the Results tab underneath Output Data.

Note:    The worksheets produced depend on the analysis type and model settings.

Dosing Used 

The dosing regimen specified in the Dosing panel.

Exclusions 

Any excluded data points specified in the Slopes panel.

Final Parameters 

Estimates of the final parameters for each level of the sort variable, including times and areas above (“TimeHigh”), in (“TimeBetween”) and below (“TimeLow”) the therapeutic response (AUCHigh, AUCLow, etc.). Parameter names that include “Inf” are extrapolated to infinity using estimated Lambda Z.

Final Parameters Pivoted 

The same as Final Parameters but with one parameter per column to conveniently perform further analysis on individual parameters.

Partial Areas 

Lists start and end times used to define the partial areas under the curve.

Plot Titles 

The title of each graph in the output.

Slopes Settings 

The settings specified for the Terminal elimination phase. It includes the start and end time for each defined time range, excluded points, fit method used and whether the time range was set by the System or the User.

Summary Table 

The sort variables, X variable, points included in the regression for Lambda Z (noted with *), Y variable, predicted Y for the regression, residual for the regression, area under the curve (AUC), area under the moment curve AUMC and the weight used for the regression.

Therapeutic Response 

Lists the lower and upper boundaries used to define the therapeutic response windows.

User Defined Computed Y 

List of user-entered time or X values and the concentration or Y values. The Type column indicates if the value was Observed or Computed by interpolation.

User Defined Parameters 

List of any user-defined parameters in the User Defined Parameters tab.

User Defined Parameters Pivoted 

The same as User Defined Parameters but with one parameter per column, to conveniently perform further analysis on individual parameters.


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