Vascular

Vascular flow

Use a vascular flow to represent blood flow in physiologically based PK models. This flow can connect PK compartments representing organs or other areas into circuits of blood flow. The flow rate between organs is represented by the variable Q.

Insert a Vascular flow by selecting Insert > PBPK > Vascular Flow from the right-click menu.

Select the first compartment of the flow.

Select the second compartment of the flow.

Note: A Vascular Flow should connect a central or a peripheral compartment. It should not be used to connect an elimination or an absorption compartment.

With the Vascular Flow selected, press the Draw button multiple times to toggle through the options for drawing the PK flow in the Graphical model interface.

Diagonal: Draws the diagonal flow.

Horizontal First: Draws the flow horizontally from the first compartment.

Vertical First: Draws the flow vertically from the first compartment.

In the CL field, enter a name for the input variable or use the default.