Results

The Semicompartmental model object generates four charts, one worksheet, and one text file.

Up to four plots are created for each profile. Each profile’s plot is displayed on its own page in the Results tab. Click the page tabs at the bottom of each plot panel to view the plots for individual profiles. If drug effect data is included in the dataset, Effect vs Ce and Effect vs Cp plots are also created.

Ce vs Time: Estimated effect site concentration vs. time.

Cp vs Time: Plasma concentration vs. time.

Effect vs Ce: Drug effect vs. the estimated effect site concentration.

Effect vs Cp: Drug effect vs. plasma concentration.

A text file called Settings is also created. It lists the user-specified settings in the Semicompartmental object

The Semicompartmental object creates a worksheet called Results. This worksheet contains: sort variables (if any are used), time points used in the study, drug concentration levels in blood plasma, Ce (estimated effect site concentration), effect data (if included). Any units associated with the time and concentration columns in the input data are carried through to the semicompartmental modeling output.