Running NLME Engines in Command Line Mode

The Pharmacometrics Modeling Language (PML) supports model building through a text-based modeling language that allows models to be described, fitted, and simulated.

The PML language supports specification of input and/or output data, trial related settings such as dosing and treatment sequence, as well as flexible model definitions for PK/PD and general Nonlinear Mixed Effects (NLME) modeling including survival analysis and modeling of categorical responses.

PML includes the necessary structures for seamless integration of modeling with trial simulation and related analyses. PML draws on established practices in R and NONMEM to make PML user-friendly for people familiar with those software packages.

Phoenix users do not need to have Phoenix running in order to run PML models from the command line. When Phoenix is installed, the files necessary to run PML models from the command line are also installed.

This section covers the following topics, describing how to operate the NLME engine in Windows command line mode using batch scripts named RunNLME.bat and RunNLMEMPI.bat.

Requirements

PML and multi-processor or multi-core computers

Install the executables and examples

Basic command line syntax

Input files

Running QRPEM in command line mode


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