Available for Indirect Response, PK, and PK/PD Linked Models only, the Dosing panel allows typing or mapping dosing data for the different models. The Dosing panel mapping columns change depending on the PK model type selected in the Model Selection tab. Required input is highlighted orange in the interface.
If multiple sort variables have been mapped in the Main Mappings panel, the Select sorts dialog is displayed for selecting the sort variables to include in the internal worksheet. Required input is highlighted orange in the interface.
None: Columns mapped to this context are not included in any analysis or output.
Sort: Categorical variable(s) identifying individual data profiles.
Time: The time of dose administration.
Dose: The amount of drug administered. Dosing units are used.
End Time: The end time of the infusion.
Infusion Length: The total amount of time for an IV infusion. Only used in conjunction with a bolus dose.
Bolus: Amount of the bolus dose.
Amount Infused: Total amount of drug infused. Dosing units are used.
Note: If the dosing data is entered using the internal dosing worksheet, and different profiles require different numbers of doses, then leave the Time, End Time, Dose, Infusion Length, Bolus, or Amount Infused cells blank for profiles that require less than the highest number of doses.
When using an internal worksheet, press Rebuild to reset the worksheet to its default state and delete all entered values.
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