Results

Select the Results tab to view the output. Loo-Riegelman object output includes worksheets, plots, and text files.

Worksheets

Dosing Used: The dosing regimen specified for the model.

Exclusions: Excluded data points.

Final Parameters and Final Parameters Pivoted: Lists the following values for each profile.

Rsq: Goodness of fit statistic for the terminal elimination phase.

Rsq_adjusted: Goodness of fit statistic for the terminal elimination phase, adjusted for the number of points used in the estimation of Lambda Z.

Lambda_z: First-order rate constant associated with the terminal (log-linear) portion of the curve. Estimated by linear regression of time vs. log concentration.

No_points_lambda_z: Number of points used in computing Lambda Z. If Lambda Z is not estimable, then no points are used.

Loo-Riegelman: Estimates for each profile, including time, concentration and cumulative AUC, amount in the peripheral compartment, amount absorbed, and relative fraction absorbed. Units are taken from the input data.

Plot Titles: Lists the title of each Observed Y and Predicted Y vs X plot.

Summary: Details for fitting Lambda Z. Not included for Loo-Riegelman with user-specified AUC¥.

Plots

Observed Y and Predicted Y vs X: Plot of the Lambda Z fit. This plot group is not created if AUC¥ is user-specified or if Lambda Z is user-specified.

Relative Fraction Absorbed: Relative fraction absorbed vs time.

Text Files

Core output: Settings, summary table, and final parameters.

Settings: Mappings and option settings.

Double-click a plot in the Results tab to edit it. (See “Plot Options tab” in the Phoenix Plot object section for editing options.)