Output from deconvolving the data will have a prefix of “Vivo.Deconvolution.” (except the Deconvolution Input worksheet).
Worksheets
Deconvolution Input
Dosing: The dosing regimen specified for modeling.
Exponential Terms: Specified exponential terms and corresponding values for each profile.
Fa-avg: Fa-Avg plot data
Fitted Values: Predicted data for each profile.
Parameters: The smoothing parameter delta and absorption lag time for each profile.
Values: Time, input rate, cumulative amount (Cumul_Amt, using the dose units) and fraction input (Cumul_Amt/test dose or, if no test doses are given, then fraction input approaches one) for each profile.
Plots
Cumulative Input Plot
Fa-Av: Fa-Avg overlaid. Average fraction absorbed by formulation. For the chart, Fabs grouped by subject with Fabs_avg overlaid and sorted by formulation. Not created if the Data already deconvolved and averaged option is selected, or if no sort variables are selected in the InVivo settings tab.
Fa-Av By Profile: Fa-Avg plot by profile. Fabs grouped by formulation, vs. time, and sorted by profile. Not created if the Data already deconvolved and averaged option is selected, or if no sort variables are selected in the InVivo tab.
Fitted Curves Plot: Observed time-concentration data vs. the predicted curve.
Input Rates Plot: Rate of drug input vs. time.
Text Files
Fa-avg: Mappings and option settings for Fa-Avg calculations.
Settings: Mappings and option settings.
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