ASCII_user_model_for

ASCII user model for correlations

A custom model for an IVIVC correlation need only include the parameter definitions and model equations. No other statements are required.

From the # parameters menu in the Correlation settings tab, select the number of model parameters.

In the Correlation Estimates panel, enter an initial value for each model parameter.

Edit the statements in the Correlation Code panel to reflect the model. Use the ASCII model syntax and the following keywords that are specific to IVIVC:

IVINTERP(): This function interpolates dissolution data. A common usage is for X to be the in vivo time, and X is then scaled or shifted by model parameters to yield an in vitro time, which is called T. IVINTERP is then used to interpolate the dissolution data to find the dissolution at time T. The first and last values in the dissolution data are used when T is respectively before or after the time range of the dissolution data.

DOSEVIVO: This variable contains the dose amount for each formulation. The wizard will translate this variable into the DTA array that is part of the modeling language.