User defined parameters

Any user defined parameters will be computed and reported in the User Defined Parameters and User Defined Parameters Pivoted worksheets. The worksheets include entries for Sort, Carry, parameter name, unit, and estimated value. A User Defined Parameters Pivoted worksheet will include the pivoted form of the User Defined Parameters worksheet.

C<time value>: For Plasma models with user-defined times only, one column per requested time value. (For plasma models, a computed concentration at time zero will be reported as the parameter C0_0, since C0 is already used for the initial concentration measurement.)

Y<x-value>: For Drug Effect models with user-defined x-values only, one column per requested x-value.

<user-defined name>: Parameter defined using the User Defined Parameters tab.

References

Holder (2001). “Comments on Nedelman and Jia's extension of Satterthwaite's approximation applied to pharmacokinetics.” J Biopharm Stat 11(1–2):75–9.

Nedelman and Jia (1998). “An extension of Satterthwaite's approximation applied to pharmacokinetics.” J Biopharm Stat 8(2):317–28.