Summary Statistics

During automation runs, Phoenix WinNonlin analysis generates summary statistics that can be included in tabular and graphical output. The following table lists all available statistics, their display name, a brief description, and default precision selected. The AutoPilot Toolkit administrator can filter the list to make only certain summary statistics available to the user.

The precisions listed below, in decimal places (dec) or significant figures (sig), are used to display the values in tabular output. Some of the summary statistics are defaulted (can be configured) for tables and graphs, but these are on a table by table or graph by graph basis.

Summary Statistic and Display Name	Description	Default Precision Type/Digits
N	Number of observations with non-missing data	dec/0
NMiss	Number of observations with missing data	dec/0
NObs	Number of observations	dec/0
Mean	Arithmetic Average	Per PK parameter
SD	Standard Deviation	Per PK parameter
SE	Standard Error	Per PK parameter
Variance	Unbiased sample variance	Per PK parameter
Min	Minimum	Per PK parameter
Median	Median	Per PK parameter
Max	Maximum	Per PK parameter
Range	Range of values (maximum value minus minimum value)	Per PK parameter
Percentiles1	The Pth percentile divides the distribution at a point such that P percent of the distribution are below this point.	Per PK parameter
CV%	Coefficient of Variation	dec/0
Geometric Mean	Geometric Mean	Per PK parameter
Harmonic Mean	Reciprocal of the arithmetic mean of the reciprocals of the observations	Per PK parameter
Mean of Logs	Arithmetic average of the natural logs of the observations	Per PK parameter
SD of the Logs	Arithmetic average of the natural logs of the observations	Per PK parameter
Geometric CV%	Geometric coefficient of variation	dec/0
95% Cl Lower Mean	Lower limit of an 95% confidence interval for the mean	Per PK parameter
95% Cl Upper Mean	Upper limit of an 95% confidence interval for the mean	Per PK parameter
95% Cl Lower Var	Lower limit of an 95% confidence interval for the variance	Per PK parameter
95% Cl Upper Var	Upper limit of an 95% confidence interval for the variance	Per PK parameter
Skewness	Coefficient of skewness	Per PK parameter
Kurtosis	Coefficient of excess	Per PK parameter
Pseudo SD	Jackknife estimate of the standard deviation of the harmonic mean.	Per PK parameter
K-S p-value	Kolmogorov-Smirnov normality test p value	Per PK parameter
Lower 68% bound	Lower range value based on one standard deviation from the geometric mean	Per PK parameter
Upper 68% bound	Upper range value based on one standard deviation from the geometric mean.	Per PK parameter

All the summary statistics are available for display in tabular output. For graphical output, only the following summary statistics are available for summary terms:

•mean

•median

•geometric mean

•harmonic mean

Only the following are available for error terms in graphical output:

•SD

•SE

•variance

•min/max

•68% Range